Hormonal Health
Kisspeptin
Kisspeptin-10 (Metastin 45-54)
Last updated: March 2026
Sequence
10 amino acids (active fragment)
Origin
Naturally occurring neuropeptide
Available From
1 suppliers
Forms
1 types
Key Benefits
1
Master regulator of reproductive hormones2
Stimulates GnRH and LH release3
Studied for fertility treatment4
May support natural testosterone productionHow It Works
Kisspeptin is a neuropeptide that acts as the master upstream regulator of the hypothalamic-pituitary-gonadal (HPG) axis. It stimulates GnRH neurons in the hypothalamus, which triggers the release of LH and FSH from the pituitary. This cascade regulates sex hormone production (testosterone, estrogen). Kisspeptin-10 is the shortest active fragment commonly used in research.
Research Highlights
๐Master regulator of puberty onset and reproductive function
๐Stimulates physiological LH pulses (unlike hCG)
๐Clinical trials for IVF show improved oocyte maturation
๐Studied as an alternative trigger for egg retrieval in IVF
๐May diagnose and treat hypothalamic amenorrhea
Available Forms
- Lyophilized powder for injection
Research Dosing
Clinical studies use 1.6-12.8nmol/kg IV or subcutaneous. Research protocols typically use 100-500mcg subcutaneous.
โ ๏ธ For research reference only. Not medical advice.
Legal Status
Kisspeptin is available for research purposes. Used in clinical trials for fertility. Not FDA-approved as a drug. Not a controlled substance.
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lyophilized powder ยท 10mg ยท โ
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