Dihexa
Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide)
Last updated: March 2026
Key Benefits
How It Works
Dihexa is a synthetic peptide derived from angiotensin IV that acts as a hepatocyte growth factor (HGF) receptor agonist. It promotes synaptogenesis (new synapse formation) and neuronal connectivity at extraordinarily low concentrations (picomolar range). Researchers at Washington State University found it 10 million times more potent than BDNF in promoting new neural connections.
Research Highlights
Available Forms
- Lyophilized powder for injection
- Oral capsules (research)
Research Dosing
Research protocols use very low doses due to extreme potency: 10-20mg subcutaneous or oral. Animal studies used 2mg/kg intranasal.
⚠️ For research reference only. Not medical advice.
Legal Status
Dihexa is available for research purposes. Not FDA-approved. Not a controlled substance. Limited human safety data available.
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