Nootropic
Semax
Semax
Last updated: March 2026
Sequence
7 amino acids
Origin
Synthetic ACTH(4-7) analogue
Available From
9 suppliers
Forms
2 types
Key Benefits
1
May enhance cognitive performance2
Studied for neuroprotective effects3
Supports BDNF expression4
Potential focus enhancementHow It Works
Semax is a synthetic peptide analog of ACTH(4-7) developed by the Institute of Molecular Genetics (Russian Academy of Sciences). It increases brain-derived neurotrophic factor (BDNF) levels and modulates the expression of BDNF and its receptor trkB in the hippocampus. Unlike ACTH, it has no steroidogenic or hormonal activity.
Research Highlights
📄Approved in Russia for cognitive disorders and stroke recovery
📄Studies show significant BDNF increase in hippocampus
📄Research demonstrates improved attention and memory
📄Clinical use in Russia for optic nerve diseases
Available Forms
- Nasal spray
- Lyophilized powder
Research Dosing
200-600 mcg intranasally in research protocols
⚠️ For research reference only. Not medical advice.
Legal Status
Approved medication in Russia and Ukraine. Research chemical elsewhere. Not FDA-approved.
Check legal status by country →Compare Prices
Full comparison →B
BuyDeus
lyophilized powder · · —
70
Good$15.00
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R
Regen Peptide Solutions
lyophilized powder · 11mg · —
70
Good$29.99
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B
Biotech Peptides
lyophilized powder · 25mg · —
65
Fair$53.00
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B
Biotech Peptides
lyophilized powder · 25mg · —
65
Fair$53.00
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S
Synthagen Labs
lyophilized powder · · —
50
Fair$56.99
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C
Core Peptides
lyophilized powder · 25mg · —
65
Fair$63.00
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