Anti-Aging
NAD+
Nicotinamide Adenine Dinucleotide
Last updated: March 2026
Sequence
Dinucleotide (not a peptide)
Origin
Present in all living cells
Available From
8 suppliers
Forms
4 types
Key Benefits
1
Essential coenzyme for cellular metabolism2
Studied for anti-aging properties3
Supports cellular energy production4
May activate sirtuinsHow It Works
NAD+ is a coenzyme found in every living cell. It plays a critical role in energy metabolism, DNA repair, and cell signaling. NAD+ levels decline with age, and this decline is associated with various age-related conditions. Supplementation aims to restore youthful NAD+ levels to support cellular function and activate longevity pathways like sirtuins.
Research Highlights
📄David Sinclair's research at Harvard on NAD+ and aging
📄Studies show NAD+ decline correlates with aging markers
📄Research on sirtuin activation and longevity pathways
📄Clinical trials on NAD+ precursors (NMN, NR) showing safety
Available Forms
- Sublingual tablets
- Nasal spray
- IV infusion
- Lyophilized powder
Research Dosing
250-500mg daily (oral) in research protocols
⚠️ For research reference only. Not medical advice.
Legal Status
Available as a dietary supplement in most countries. NAD+ precursors (NMN, NR) widely available as supplements.
Check legal status by country →Compare Prices
Full comparison →C
Core Peptides
lyophilized powder · 100mg · —
65
Fair$43.00
—
C
Core Peptides
lyophilized powder · 100mg · —
65
Fair$43.00
—
A
Apollo Peptide Sciences
lyophilized powder · 500mg · —
60
Fair$69.99
—
A
Apollo Peptide Sciences
lyophilized powder · 500mg · —
60
Fair$69.99
—
B
Beyond Peptides
lyophilized powder · · —
80
Good$100.10
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B
Beyond Peptides
injectable · · —
80
Good$109.11
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